cidrap.umn.edu - by Lisa Schnirring  - September 2, 2016

WHO panel cites virus spread, research gaps
CLICK HERE - WHO - Fourth meeting of the Emergency Committee under the International Health Regulations (2005) regarding microcephaly, other neurological disorders and Zika virus 

CDC funds for microcephaly, birth defects
CLICK HERE - CDC awards $2.4 million to five jurisdictions to fight Zika

The World Health Organization (WHO) announced today that its Zika emergency committee, which met yesterday, has recommended keeping the public health emergency in place, as the US Centers for Disease Control and Prevention (CDC) announced $2.4 million in funding to help five of the nation's most populated cities detect and manage Zika-related birth defects.

CDC-Colombia effort, Singapore cases, brain cell infection
In other new Zika developments, the CDC announced a formal research collaboration with Colombia, Singapore reported more Zika cases, and researchers revealed possible differences in brain cell infections between the two Zika lineages.

Zulay Balza, right, recovering from Guillain-Barre syndrome in February at a hospital in Colombia. Ms. Balza did not show symptoms of the Zika virus; only one in five infected people do. Credit Ricardo Mazalan/Associated Press

CLICK HERE - NEJM - Zika Virus and the Guillain–Barré Syndrome — Case Series from Seven Countries

nytimes.com - by Catherine Saint Louis - August 31, 2016

In seven countries that recently experienced Zika outbreaks, there were also sharp increases in the numbers of people suffering from a form of temporary paralysis, researchers reported Wednesday.

The analysis, published online in The New England Journal of Medicine, adds to substantial evidence that Zika infections — even asymptomatic ones — may bring on a paralysis called Guillain-Barré syndrome.

(READ COMPLETE ARTICLE)

submitted by Albert Gomez

Doctoral students Emily Lee, Yichen Cheng and Sarah Ogden played a key role in conducting Zika research in Professor Hengli Tang’s laboratory.

CLICK HERE - RESEARCH - Nature Medicine - Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen

news.fsu.edu - by Kathleen Haughney - August 29, 2016

A team of researchers from Florida State University, Johns Hopkins University and the National Institutes of Health has found existing drug compounds that can both stop Zika from replicating in the body and from damaging the crucial fetal brain cells that lead to birth defects in newborns.

One of the drugs is already on the market as a treatment for tapeworm. . . .

. . . Their work is outlined in an article published Monday by Nature Medicine.

(READ COMPLETE ARTICLE)

Rules for distribution of mosquito repellent to women and girls on Medicaid can make getting it difficult, as rest of gulf coast similarly lags behind spread of virus

theguardian.com - Jessica Glenza and Nicole Puglise - August 26, 2016

Attempts to provide poor, pregnant women in Texas with mosquito repellent to avoid possible Zika infections are off to a slow start.

Two weeks after the state announced that mosquito repellent would be given out to women and girls on Medicaid, only 1,200 cans have been distributed, equivalent to less than 1% of the roughly 134,000 pregnant women eligible for the product.

(READ COMPLETE ARTICLE)

CLICK HERE - Texas Health and Human Services Commission - Texas Becomes First State to Issue Standing Order for Mosquito Repellent to Fight Zika - August 15, 2016

CLICK HERE - Texas Health and Human Services Commission - Medicaid Will Pay for Mosquito Repellent to Fight Zika - August 3, 2016

fda.gov - August 26, 2016

As a further safety measure against the emerging Zika virus outbreak, today the U.S. Food and Drug Administration issued a revised guidance recommending universal testing of donated Whole Blood and blood components for Zika virus in the U.S. and its territories.

“There is still much uncertainty regarding the nature and extent of Zika virus transmission,” said Peter Marks, M.D., Ph.D., director of the FDA’s Center for Biologics Evaluation and Research. “At this time, the recommendation for testing the entire blood supply will help ensure that safe blood is available for all individuals who might need transfusion.”

Dr. Angela Rocha shows brain scans of a baby born with microcephaly at the Oswaldo Cruz Hospital in Recife, Brazil.  FELIPE DANA/AP

CLICK HERE - NEJM - Prolonged Shedding of Zika Virus Associated with Congenital Infection

CLICK HERE - Radiology - Congenital Brain Abnormalities and Zika Virus: What the Radiologist Can Expect to See Prenatally and Postnatally

statnews.com - by Helen Branswell - August 24, 2016

A new report from Brazil raises questions about whether the Zika virus can continue to damage an infected infant’s brain after birth.

An infant in Sao Paulo whose mother was infected late in her second trimester was born without any visible birth defects. But testing showed the baby had the Zika virus in his blood; the virus remained in his system for at least a couple of months.

At six months, it became apparent that the child had suffered Zika-related brain damage.

(READ COMPLETE ARTICLE)

Aedes aegypti mosquitoes are seen inside Oxitec laboratory in Campinas, Brazil, February 2, 2016.
REUTERS/Paulo Whitaker/File Photo

CLICK HERE - STUDY - Radiology - Congenital Brain Abnormalities and Zika Virus: What the Radiologist Can Expect to See Prenatally and Postnatally

reuters.com - Reporting by Julie Steenhuysen; Editing by Dan Grebler - August 23, 2016

A report released on Tuesday shows in graphic detail the kind of damage Zika infections can do to the developing brain - damage that goes well beyond the devastating birth defect known as microcephaly, in which the baby's head is smaller than normal.

The current Zika outbreak was first detected last year in Brazil, where the virus has been linked to more than 1,800 cases of microcephaly, which can cause severe developmental problems.

Prior research has shown the Zika virus attacks neural progenitor cells - a type of stem cell that develops into different types of nerve or brain cells.

Ueslei Marcelino / Reuters

CLICK HERE - RESEARCH - Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation

New research has found evidence the mosquito-borne virus can adversely affect cells necessary for replenishing damaged neurons.

theatlantic.com - by Marina Koren - August 19, 2016

Zika is understood to pose the greatest threat to pregnant women and their fetuses, which can be born with severe brain defects if infected with the mosquito-borne virus. But new research suggests Zika may damage adult brains, too, giving scientists another thread to follow in their attempts to understand the virus as the number of infections continues to rise in South America, the Caribbean, and elsewhere.

U.S. researchers have found evidence that a certain kind of brain cell present in newborns that remains in some amounts in adulthood can be susceptible to Zika infection, according to a study published Thursday in the journal Cell Stem Cell.

(READ COMPLETE ARTICLE)

ALSO SEE RELATED ARTICLES WITHIN THE LINKS BELOW . . .

Image: A photograph of a baby wearing a diaper. Jerome Scholler / Shutterstock

theatlantic.com - August 18th 2016 - Adrienne LaFrance

Among the many mysteries that have vexed scientists about the ongoing Zika epidemic is the question of how, in pregnant women, the virus manages to cross the maternal-fetal barrier.

A woman’s body is usually quite good at protecting her growing baby. There are biological blockades to prevent the transmission of viruses to a fetus through the bloodstream, by way of the placenta; the same path for the nutrients and oxygen that sustain a developing baby.

(VIEW COMPLETE ARTICLE)

kfdm.com - by Staff - August 12, 2016

From Orange County Mosquito Control District:

Orange County Mosquito Control District has been informed by the Texas Department of Health that a collection of mosquitoes from Orange County tested positive for West Nile virus. The mosquitoes testing positive for WNV were collected on August 2nd from an area on the west side of the County - North of IH-10, East of HWY 105, West of Doty Rd. and South of Sawmill Rd., in Vidor. This is the 1st sample of mosquitoes testing positive for the West Nile virus in Orange County in 2016. This information tells us that the virus is cycling between the birds and the mosquitoes in the area. So, it is important for everyone to take personal protective measures to protect themselves from mosquito bites regardless of what area it is that they live in throughout the county. Currently, West Nile virus activity in Texas is as follows: Mosquitoes Collections 903, Bird’s 1, Horses 4, Humans 37, Total 945. West Nile virus activity has been detected in 26 counties in Texas so far this year.

Treatments in the area have been increased and we are following up with additional mosquito collections and the testing of samples from the area to determine whether or not viral activity still exists. These procedures will continue until we receive negative results from the T.D.H. labs.

Zika virus is classified as biological safety level (BSL) 2 pathogen.

Revised diagnostic testing for Zika, chikungunya, and dengue viruses in US Public Health Laboratories - February 7, 2016
(see page 2, of 6 page .PDF file)
https://www.cdc.gov/zika/pdfs/denvchikvzikv-testing-algorithm.pdf

Associated Press - by Danica Coto - August 5, 2016

SAN JUAN, Puerto Rico (AP) -- Health officials announced Friday that an elderly person infected with Zika has died in Puerto Rico as the U.S. territory battles what federal authorities call a silent epidemic.

The victim was a 75-year-old man who was hospitalized and died from health ailments unrelated to Zika, according to Health Secretary Ana Rius. . . .

. . . The first Zika-related death was reported in late April and involved a 70-year-old man from the San Juan metro area. He suffered internal bleeding after developing a condition in which antibodies that formed in response to a Zika infection began attacking blood platelet cells. At the time, Rius said there were three other cases of the condition known as severe thrombocytopenia and that those patients recovered.

CLICK HERE - READ COMPLETE ARTICLE

(See additional supporting documentation within the links below)

CLICK HERE - Zika virus: first American dies of complications linked to disease

Image: Lake Tahoe is warming faster than ever thanks in large part to human-caused climate change.   (Photo: CelsoDiniz, Getty Images/iStockphoto)

khou.com - July 30th 2016 - Benjamin Spillman

The biggest alpine lake in North America is warming faster than ever thanks in large part to a changing global climate.

That’s according to scientists who study Lake Tahoe to produce reports on everything from water temperature to clarity to invasive species.

The latest data in the State of the Lake report shows average water temperature in the lake increased nearly half a degree in one year.

by Philip K. Stoddard, Ph.D. - Mayor of South Miami & Professor of Biological Sciences - Florida International University

Tactics for keeping out Zika

1. Keep Aedes aegypti from breeding in your house and yard by eliminating all standing water (see checklist on other side).

2. Keep Aedes aegypti out of your house. Window and screens should have no gaps or holes. Move and empty your pet’s water dish every day when they don’t need it.

3. Avoid getting bitten outdoors.

Insect repellants with DEET repel flying mosquitoes and prevent them from biting. Long sleeves and trousers help. Electric fans help – Aedes aegypti is a weak flyer and likes still air.

4. Don’t let your neighbors down.

One person can provide mosquitoes for the whole neighborhood by not taking the precautions listed here.

CLICK HERE FOR ADDITIONAL IMPORTANT INFORMATION (2 page .PDF file)

Florida governor asks CDC to activate emergency response team following increase in Zika cases

CLICK HERE - CDC - Zika Virus - Advice for people living in or traveling to Wynwood, a neighborhood in Florida

weather.com - by Eric Chaney - August 1, 2016

The CDC issued an advisory Monday that says pregnant women should not travel to a so-called Zika "transmission area" near Miami, the same day governor Rick Scott announced there are 10 new infections of the Zika virus likely transmitted by mosquitoes, bringing the total in the state to 14.

The governor called on the Centers for Disease Control and Prevention to activate an Emergency Response Team to assist the Florida Department of Health and other partners in their investigation, sample collection, and mosquito control efforts.

(READ COMPLETE ARTICLE)