CLICK HERE - CDC - MMWR - Preliminary Report of Microcephaly Potentially Associated with Zika Virus Infection During Pregnancy — Colombia, January–November 2016

CLICK HERE - Columbia - INSTITUTO NACIONAL DE SALUD - Zika

nytimes.com - by Donald G. McNeil, Jr. - December 10, 2016

Colombia, which suffered a Zika epidemic that peaked in February, has reported four times as many cases of babies born with microcephaly this year as it did in 2015, providing more proof that the Zika virus causes brain damage in infants.

Because births of microcephalic infants peaked five months after the epidemic did, at about nine times the numbers of the previous July, scientists feel sure that the greatest risk is to babies whose mothers were infected during their first trimesters or early in their second.

The numbers were reported in a study released Friday by the Centers for Disease Control and Prevention and conducted jointly by scientists from the C.D.C. and Colombia’s national health institute.

Infection of developing human brain with the Zika virus (green) highlights susceptibility of radial glial cells during fetal development. Image by Elizabeth Di Lullo

CLICK HERE - STUDY - PNAS - Zika virus cell tropism in the developing human brain and inhibition by azithromycin

ucsf.edu - by Laura Kurtzman - November 29, 2016

Working in the lab, UC San Francisco researchers have identified fetal brain tissue cells that are targeted by the Zika virus and determined that azithromycin, a common antibiotic regarded as safe for use during pregnancy, can prevent the virus from infecting these cells . . .

 . . . In the new study, published online Nov. 29, 2016, in the Proceedings of the National Academy of Sciences (PNAS), the UCSF researchers determined that the Zika virus preferentially infects brain cells with an abundance of a protein called AXL, which spans the outer cell membrane of several cell types and serves as a gateway for the invading virus . . . 

CLICK HERE - Texas Department of State Health Services - Texas Announces Local Zika Virus Case in Rio Grande Valley

reuters.com - by Julie Steenhuysen - November 28, 2016

Texas health officials on Monday reported the state's first case of Zika likely spread by local mosquitoes, making Texas the second state within the continental United States to report local transmission of the virus that has been linked to birth defects.

The case involved a woman living in Cameron County near the Mexico border who is not pregnant, the Texas Department of State Health Services said.

Pregnancy is the biggest concern with Zika because the virus can cause severe, life-long birth defects, including microcephaly, in which a child is born with an abnormally small head, a sign its brain has stopped growing normally . . .

 . . . In adults, Zika infections have also been linked to a rare neurological syndrome known as Guillain-Barre, as well as other neurological disorders.

(READ COMPLETE ARTICLE)

A 1-year-old child, one of the patients in a new study, showed clear signs of microcephaly, but also had good eye contact. Credit van der Linden V, Pessoa A, et al. MMWR: 11.22.2016

nytimes.com - by Pam Belluck - November 22, 2016

It is the news that doctors and families in the heart of Zika territory had feared: Some babies not born with the unusually small heads that are the most severe hallmark of brain damage as a result of the virus have developed the condition, called microcephaly, as they have grown older.

The findings were reported in a study of 13 babies in Brazil that was published Tuesday in Morbidity and Mortality Weekly Report. At birth, none of the babies had heads small enough to receive a diagnosis of microcephaly, but months later, 11 of them did . . . 

 . . . The new study echoes another published this fall, in which three babies were found to have microcephaly later in their first year.

(READ COMPLETE ARTICLE)

Transmission electron micrograph (TEM) of Zika virus. Credit: Cynthia Goldsmith/Centers for Disease Control and Prevention

sciencedaily.com - American Association of Pharmaceutical Scientists - November 15, 2016

Research being presented today at the 2016 American Association of Pharmaceutical Scientist (AAPS) Annual Meeting and Exposition, which is taking place Nov. 13 -17 in Denver, found that under certain conditions, the Zika virus can live for several hours on hard non-porous surfaces and still be highly contagious, but that some commonly used disinfectants are extremely effective in killing the virus. The research may have important infection control implications for both consumers and those who work in healthcare or lab settings.

(READ COMPLETE ARTICLE)

ALSO SEE SUPPORTING DOCUMENTATION WITHIN THE LINKS BELOW . . .

A researcher holds a tray of Zika virus growing in cells at Washington University School of Medicine in St. Louis. No treatments exist to block Zika virus in a pregnant woman from infecting her fetus and potentially causing severe birth defects. But now, researchers report that they have identified a human antibody that prevents -- in pregnant mice -- the fetus from becoming infected and damage to the placenta. The antibody also protects adult mice from Zika disease.  Photo: Huy Mach

CLICK HERE - Nature - Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

nbcnews.com - by Maggie Fox - November 7, 2016

Researchers reported two steps toward fighting the Zika virus Monday — one from a team that has found a potential way to protect unborn babies from the virus, and a second from a team that announced the start of human trials of a new vaccine.

Neither offers immediate relief against the epidemic of Zika that has swept across the Americas and the Caribbean and parts of Asia, but they both provide hope of eventually being able to protect pregnant women and their babies from the infection.

Mosquito vector Aedes aegypti mosquitoes. Credit: NIAID

CLICK HERE - Implication of vaccination against dengue for Zika outbreak

yfile.news.yorku.ca - October 31, 2016

Vaccinating against dengue fever could increase outbreaks of Zika, suggests new research out of York University and Xi’an Jiaotong University in China.

The research identifies a potentially serious public health concern. More than a third of the world’s population lives in areas where dengue is endemic and cases of co-infection with Zika have already been reported.

(READ COMPLETE ARTICLE)

Early data from new lab tests reopen question of non-Aedes vectors

SPREADING NEWS  The controversial idea that a Culex mosquito (shown) can spread Zika is getting some reconsideration as new data are emerging from separate labs.

sciencenews.org - by Susan Milius - September 28, 2016

ORLANDO, Fla. — New evidence from separate labs supports the controversial idea that an overlooked and unexpected Culex mosquito might spread Zika virus.

The southern house mosquito, Culex quinquefasciatus, is common in the Americas. Constância Ayres, working with Brazil’s Oswaldo Cruz Foundation in Recife, previously surprised Zika researchers with the disturbing proposal that this mosquito might be a stealth spreader of Zika. But two U.S. research groups tested the basic idea and couldn’t get the virus to infect the species.

Now, preliminary results from Ayres’ and two other research groups are renewing the discussion.

(READ COMPLETE ARTICLE)

After nearly seven months of bickering and finger-pointing, Congress on Wednesday agreed to allocate $1.1 billion to help fight the spread and effects of the Zika virus.

The deal is part of a broader agreement to continue to fund the government after the fiscal year ends on Friday and the current budget expires.

It brings to an end a partisan fight that has had the unusual effect of delaying funding to deal with what all sides agree is a public health emergency.

Congress Stops Bickering And Approves $1.1 Billion To Fight Zika
http://www.npr.org/sections/health-shots/2016/09/28/495806979/congress-ends-spat-over-zika-funding-approves-1-1-billion?utm_term=nprnews

Congress passes funding bill averting government shutdown
http://www.reuters.com/article/us-usa-congress-idUSKCN11Y1MJ

Congress clears stopgap spending bill, $1.1B to fight Zika
http://unb.com.bd/article/congress-clears-stopgap-spending-bill-dollar11b-to-fight-zika

healio.com - September 25, 2016

CLICK HERE - Quest Diagnostics - Zika Virus Infection - Important Testing Information

Quest Diagnostics announced a new antibody test service — based on the Zika immunoglobulin M antibody capture enzyme-linked immunosorbent assay developed by the CDC — is available for the detection of infection associated with Zika virus, according to a news release.

The CDC licensed the test to Quest Diagnostics and other national reference laboratories to help combat Zika in the United States. Quest will offer access to Zika virus antibody and molecular laboratory test services through 2,300 service centers for people in the U.S., Puerto Rico and other U.S. territories.

(READ COMPLETE ARTICLE)

Photograph of Port Vincent and the Amite River on Sunday, taken during a NOAA Remote Sensing Division aerial photography mission. (NOAA Remote Sensing Division)

AN EXPANDING LIST OF INFORMATION ON THE FLOOD EVENT ALONG THE GULF COAST (CLICK ON THE LINKS BELOW)

CLICK HERE - MAP - LA Flood Rescue Efforts - South Louisiana Stranded - Addresses for those in need of rescue in South Louisiana

CLICK HERE - LA Flood Rescue Efforts - Submit your rescue status update

CLICK HERE - Louisiana Department of Health - Emergency Preparedness - Zika Information and Resources

CLICK HERE - Louisiana - Office of the Governor - Registration Details Released for Shelter at Home Program

CLICK HERE - FEMA - Disaster Assistance (1 page .PDF file)

Culex mosquitoes do not appear to transmit Zika virus, according to research at Kansas State University's Biosecurity Research Institute.

CLICK HERE - RESEARCH - Culex Species Mosquitoes and Zika Virus

k-state.edu - September 22, 2016

A Biosecurity Research Institute study has found important results in the fight against Zika virus: Culex mosquitoes do not appear to transmit Zika virus.

Researchers at Kansas State University's Biosecurity Research Institute studied Culex species mosquitoes from across the country, including Vero Beach in Florida, which is near Miami-Dade County where mosquitoes are spreading Zika virus. 

The research, "Culex species mosquitoes and Zika virus," appears in the journal Vector-Borne and Zoonotic Diseases and involves researchers from Rutgers University, the University of Florida and the U.S. Department of Agriculture.

(READ COMPLETE ARTICLE)

A baby with microcephaly at a rehabilitation centre in Recife, Brazil.  Reuters: Ueslei Marcelino

CLICK HERE - The Lancet Infectious Diseases - Association between Zika virus infection and microcephaly in Brazil, January to May, 2016: preliminary report of a case-control study

abc.net.au - AFP - September 15, 2016

Scientists are warning that the world should prepare for a "global epidemic" of microcephaly, a birth defect where a baby's head is smaller than usual, as the Zika virus spreads to new countries.

Key points:

Researchers say microcephaly epidemic will spread to all countries with Zika

Scientists recommend Zika be added to list of congenital birth infections

Not all study babies with microcephaly had abnormalities show in brain scans

The warning comes after researchers in Brazil and Britain found further evidence to link the condition with Zika virus, a connection already widely accepted in medical circles.

(READ COMPLETE ARTICLE)

Infants born with microcephaly are held by mothers at a meeting for mothers of children with special needs in Recife, Brazil.  Mario Tama/Getty Images

CLICK HERE - CDC - Emerging Infectious Diseases (EID) - Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome

npr.org - by Susan Brink - September 14, 2016

"These babies do not catch up as they grow," says Dr. Antonia Augusto Moura da Silva of the Federal University of Maranhao, Sao Luis, Brazil.

He's describing the findings from a study of 48 babies whose mothers were believed to have been infected with the Zika virus. Forty-two of the children were diagnosed with microcephaly. The study, on the early neurological growth pattern of the infants, will be published in the journal Emerging Infectious Diseases in November but was released early online.

(READ COMPLETE ARTICLE)

A new study demonstrates that Zika can affect adult brain cells in mice, suggesting that the effects of Zika could be bigger than currently presumed. (YURI CORTEZ/AFP/Getty Images)

CLICK HERE - Cell Stem Cell - Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation

CLICK HERE - Singapore - Minister of Health (MOH) - Sequencing of Zika Virus Strains From Sims Drive/ Aljunied Crescent Cluster

forbes.com - by Tim Chen - September 12, 2016

As concerns rise over the spread of the Zika virus in Southeast Asia, a new study from the Rockefeller University, published in Cell Stem Cell, found that the virus can also affect adult brain cells in mice — suggesting the potential for Zika to hold long-term neurological implications for adult humans.