Third dose of Moderna vaccine offers "substantial" improvement in protection against Omicron--NIH study

NIH study: Third dose of Moderna vaccine offers "substantial" improvement in protection against Omicron A third dose of Moderna’s Covid-19 vaccine offers protection against the Omicron variant that’s 20 times better than the antibody response of two doses, according to a study from the National Institutes of Health. By <a href="/profiles/aditi-sandal">Aditi Sangal</a>, <a href="/profiles/adrienne-vogt">Adrienne Vogt</a>, Melissa Macaya and Mike Hayes, CNN CNN

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Dr. Anthony Fauci presented a sample of the data on Wednesday during a virtual briefing by the White House Covid-19 Response Team, noting that the full study is part of a series of data that will be published on a preprint server next week.

The neutralizing activity against Omicron was “substantially low” two weeks after just two doses of vaccine, Fauci said, but there was a “substantial degree” of improvement two weeks after a third dose. The data shows that a third dose provides protection that is “well within the range of neutralizing Omicron,” he said.

This data was part of a selection of findings from in vitro studies that Fauci presented on Wednesday.

Fauci also presented data from Pfizer/BioNTech that showed a booster dose greatly improves antibody response to the Omicron variant. ...