Moderna CEO warns people may need fourth Covid shot as efficacy of boosters likely to decline over time

Moderna CEO Stephane Bancel on Thursday said the efficacy of boosters against Covid-19 will likely decline over time, and people may need a fourth shot in the fall to increase their protection.

Bancel said people who received their boosters last fall will likely have enough protection to get them through the winter, when new infections surge as people gather indoors to escape the cold.

However, Bancel said the efficacy of boosters will probably decline over the course of several months, similar to what happened with the first two doses. The Moderna chief was interviewed by Goldman Sachs during the investment bank’s health-care CEO conference.

“I will be surprised when we get that data in the coming weeks that it’s holding nicely over time — I would expect that it’s not going to hold great,” Bancel said, referring to the strength of the booster shots.   ...